AbstractAn important issue for immunologists is the difference between the two main processes that determine the mature repertoire of T-cell receptors, termed positive and negative selection. Recent papers have addressed the role of self-peptides in the process of positive selection
Positive selection of CD4+ T cells requires the interaction of the T cell receptor (TCR) of double p...
AbstractPositive selection of functional CD8+ T cells expressing an MHC class I-restricted T cell re...
Conventional and regulatory T cells develop in the thymus where they are exposed to samples of self-...
AbstractAn important issue for immunologists is the difference between the two main processes that d...
AbstractTo understand how thymic selection gives rise to T cells that are capable of major histocomp...
AbstractIn the thymus, positive and negative selection shape the T cell repertoire. It has previousl...
AbstractAlthough the thymus produces many immature thymocytes, few of these cells mature. Positive s...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractThe central event in thymic selection of T cells bearing αβ TCRs is their interaction with s...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
Adaptive immune recognition is mediated by the binding of peptide–human leukocyte antigen complexes ...
SummaryDeveloping T cells express diverse antigen receptors whose specificities are not prematched t...
AbstractThe influence of individual peptides in thymic selection was examined in H2-M− mice, in whic...
AbstractRecent studies of T-cell development in various types of mutant mouse shed new light on the ...
AbstractThe role of self-peptides in positive selection of CD4+ T cells has been controversial. We s...
Positive selection of CD4+ T cells requires the interaction of the T cell receptor (TCR) of double p...
AbstractPositive selection of functional CD8+ T cells expressing an MHC class I-restricted T cell re...
Conventional and regulatory T cells develop in the thymus where they are exposed to samples of self-...
AbstractAn important issue for immunologists is the difference between the two main processes that d...
AbstractTo understand how thymic selection gives rise to T cells that are capable of major histocomp...
AbstractIn the thymus, positive and negative selection shape the T cell repertoire. It has previousl...
AbstractAlthough the thymus produces many immature thymocytes, few of these cells mature. Positive s...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractThe central event in thymic selection of T cells bearing αβ TCRs is their interaction with s...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
Adaptive immune recognition is mediated by the binding of peptide–human leukocyte antigen complexes ...
SummaryDeveloping T cells express diverse antigen receptors whose specificities are not prematched t...
AbstractThe influence of individual peptides in thymic selection was examined in H2-M− mice, in whic...
AbstractRecent studies of T-cell development in various types of mutant mouse shed new light on the ...
AbstractThe role of self-peptides in positive selection of CD4+ T cells has been controversial. We s...
Positive selection of CD4+ T cells requires the interaction of the T cell receptor (TCR) of double p...
AbstractPositive selection of functional CD8+ T cells expressing an MHC class I-restricted T cell re...
Conventional and regulatory T cells develop in the thymus where they are exposed to samples of self-...
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