Homing DNA endonucleases are highly site-specific enzymes that initiate the transfer of mobile DNA elements. In this issue of Structure, Spiegel et al. report the structure of the I-CeuI homing enzyme and describe how a symmetric homodimeric enzyme acquired specificity for an asymmetric substrate
Homing endonucleases (HEs) typically have one of four types of catalytic domains (LAGLIDADG, GIY-YIG...
SummaryProteins of the DUF199 family, present in all Gram-positive bacteria and best characterized b...
The retargeting of protein-DNA specificity, outside of extremely modular DNA binding proteins such a...
Thesis (Ph.D.)--University of Washington, 2011Homing endonucleases, found in all forms of microbial ...
Inteins catalyze their removal from a host protein through protein splicing. Inteins that contain an...
Homing endonucleases are microbial DNA-cleaving enzymes that mobilize their own reading frames by ge...
Endonucleases are enzymes that cleave phosphodiester bonds within polynucleotide chains such as DNA ...
Homing endonuclease genes (HEGs) are selfish genetic elements that mediate their own super-Mendelian...
AbstractHoming endonucleases are classified into four families based on active site sequence motifs....
Homing endonucleases are rare-cutting enzymes that cleave DNA at a site near their own location, pre...
I-CreII is a homing endonuclease from the Cr.psbA intron of Chlamydomonas reinhardtii. It cleaves t...
12 páginas, 6 figuras, 3 tablas.Meganucleases, or homing endonucleases (HEs) are sequence-specific e...
Maintenance of genome integrity requires that branched nucleic acid molecules are accurately proces...
Inteins and introns are intervening elements that interrupt numerous essential genes and proteins in...
Mobile genetic elements are common inhabitants of virtually every genome where they can exert profou...
Homing endonucleases (HEs) typically have one of four types of catalytic domains (LAGLIDADG, GIY-YIG...
SummaryProteins of the DUF199 family, present in all Gram-positive bacteria and best characterized b...
The retargeting of protein-DNA specificity, outside of extremely modular DNA binding proteins such a...
Thesis (Ph.D.)--University of Washington, 2011Homing endonucleases, found in all forms of microbial ...
Inteins catalyze their removal from a host protein through protein splicing. Inteins that contain an...
Homing endonucleases are microbial DNA-cleaving enzymes that mobilize their own reading frames by ge...
Endonucleases are enzymes that cleave phosphodiester bonds within polynucleotide chains such as DNA ...
Homing endonuclease genes (HEGs) are selfish genetic elements that mediate their own super-Mendelian...
AbstractHoming endonucleases are classified into four families based on active site sequence motifs....
Homing endonucleases are rare-cutting enzymes that cleave DNA at a site near their own location, pre...
I-CreII is a homing endonuclease from the Cr.psbA intron of Chlamydomonas reinhardtii. It cleaves t...
12 páginas, 6 figuras, 3 tablas.Meganucleases, or homing endonucleases (HEs) are sequence-specific e...
Maintenance of genome integrity requires that branched nucleic acid molecules are accurately proces...
Inteins and introns are intervening elements that interrupt numerous essential genes and proteins in...
Mobile genetic elements are common inhabitants of virtually every genome where they can exert profou...
Homing endonucleases (HEs) typically have one of four types of catalytic domains (LAGLIDADG, GIY-YIG...
SummaryProteins of the DUF199 family, present in all Gram-positive bacteria and best characterized b...
The retargeting of protein-DNA specificity, outside of extremely modular DNA binding proteins such a...