The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive function
The p53 tumour suppressor is the most frequently mutated gene in human cancer. This transcription fa...
Summaryp53 induces cell death upon DNA damage, but this may not confer all of its tumor suppressor a...
AbstractThe tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
AbstractAlthough the p53 tumor suppressor acts in a plethora of processes that influence cellular pr...
AbstractDespite the common assumption that p53 by itself can induce apoptosis, results of a recent s...
AbstractMore than a decade ago, it was found that one of the two essential physiological functions o...
The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressi...
SummaryActivation of apoptosis through transcriptional induction of Puma and Noxa has long been cons...
While the tumor suppressor functions of p53 have long been recognized, the contribution of p53 to nu...
© 2014 Dr. Elizabeth J. ValentePublication included in thesis:Valente, L. J., Gray, D. H. D., Michal...
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The tumor suppressor p53 regulates differe...
SummaryCell-cycle arrest, apoptosis, and senescence are widely accepted as the major mechanisms by w...
Background: The p53 protein is the best studied target in human cancer. For decades, p53 has been be...
The p53 tumour suppressor is the most frequently mutated gene in human cancer. This transcription fa...
Summaryp53 induces cell death upon DNA damage, but this may not confer all of its tumor suppressor a...
AbstractThe tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
AbstractAlthough the p53 tumor suppressor acts in a plethora of processes that influence cellular pr...
AbstractDespite the common assumption that p53 by itself can induce apoptosis, results of a recent s...
AbstractMore than a decade ago, it was found that one of the two essential physiological functions o...
The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressi...
SummaryActivation of apoptosis through transcriptional induction of Puma and Noxa has long been cons...
While the tumor suppressor functions of p53 have long been recognized, the contribution of p53 to nu...
© 2014 Dr. Elizabeth J. ValentePublication included in thesis:Valente, L. J., Gray, D. H. D., Michal...
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The tumor suppressor p53 regulates differe...
SummaryCell-cycle arrest, apoptosis, and senescence are widely accepted as the major mechanisms by w...
Background: The p53 protein is the best studied target in human cancer. For decades, p53 has been be...
The p53 tumour suppressor is the most frequently mutated gene in human cancer. This transcription fa...
Summaryp53 induces cell death upon DNA damage, but this may not confer all of its tumor suppressor a...
AbstractThe tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to...
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