Publication date
May 2011
DOI Publisher
Elsevier Inc. ISSN
1534-5807 Citation count (estimate)
1Abstract
Guarani et al. (2011), reporting in Nature, identify a mechanism for fine-tuning endothelial Notch signaling by SIRT1-mediated deacetylation. This regulation is critical for vascular sprouting and raises intriguing questions about therapeutic targeting of SIRT1 in angiogenesis and the potential mechanisms that link vascular growth and energy homeostasis
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