SummaryPrior to anaphase, sister chromatids must be attached to microtubules and under tension, a condition that satisfies the spindle checkpoint. Removal of sister chromatid cohesion is predicted to cause a fall in tension. Two studies shed light on how cells avoid re-activation of the spindle checkpoint when cohesion is lost
AbstractCohesion between sister chromatids opposes the splitting force exerted by microtubules, and ...
Elaborate mechanisms have evolved which allow cells to faithfully segregate their DNA into two daugh...
Summary: The spindle assembly checkpoint (SAC) delays anaphase onset until sister chromosomes are bo...
SummaryPrior to anaphase, sister chromatids must be attached to microtubules and under tension, a co...
Sister-chromatid cohesion, thought to be primarily mediated by the cohesin complex, is essential for...
Recent high-resolution studies of kinetochore structure have transformed the way researchers think a...
The spindle assembly checkpoint (SAC) is a feedback control system that monitors the state of kineto...
When a eukaryotic cell divides, tension builds at centromeres as spindle forces pull chromosomes tow...
The spindle checkpoint ensures that newly born cells receive one copy of each chromosome by preventi...
Faithful segregation of chromosomes is a vital mitotic process that must happen every cell division ...
AbstractRecent studies have shed new light on how the physical association between sister cells is s...
SummaryBackgroundChromosome instability is thought to be a major contributor to cancer malignancy an...
Equal division of genetic information is essential to cell proliferation. In eukaryotes, the divisio...
Mitotic cell divisions ensure stable transmission of genetic information from a mother to daughter c...
During mitosis, cohesin- and condensin-based pericentric chromatin loops function as a spring networ...
AbstractCohesion between sister chromatids opposes the splitting force exerted by microtubules, and ...
Elaborate mechanisms have evolved which allow cells to faithfully segregate their DNA into two daugh...
Summary: The spindle assembly checkpoint (SAC) delays anaphase onset until sister chromosomes are bo...
SummaryPrior to anaphase, sister chromatids must be attached to microtubules and under tension, a co...
Sister-chromatid cohesion, thought to be primarily mediated by the cohesin complex, is essential for...
Recent high-resolution studies of kinetochore structure have transformed the way researchers think a...
The spindle assembly checkpoint (SAC) is a feedback control system that monitors the state of kineto...
When a eukaryotic cell divides, tension builds at centromeres as spindle forces pull chromosomes tow...
The spindle checkpoint ensures that newly born cells receive one copy of each chromosome by preventi...
Faithful segregation of chromosomes is a vital mitotic process that must happen every cell division ...
AbstractRecent studies have shed new light on how the physical association between sister cells is s...
SummaryBackgroundChromosome instability is thought to be a major contributor to cancer malignancy an...
Equal division of genetic information is essential to cell proliferation. In eukaryotes, the divisio...
Mitotic cell divisions ensure stable transmission of genetic information from a mother to daughter c...
During mitosis, cohesin- and condensin-based pericentric chromatin loops function as a spring networ...
AbstractCohesion between sister chromatids opposes the splitting force exerted by microtubules, and ...
Elaborate mechanisms have evolved which allow cells to faithfully segregate their DNA into two daugh...
Summary: The spindle assembly checkpoint (SAC) delays anaphase onset until sister chromosomes are bo...
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