AbstractIn cancer, multidrug resistance (MDR) is the simultaneous resistance of tumor cells to different natural product anticancer drugs that have no common structure. This is an impediment to the successful treatment of many human cancers. A common correlate of MDR is the overexpression of a membrane protein, P-glycoprotein. Many studies have shown that MDR can be reversed after the use of substrate analogs, called MDR modulators. However, our understanding of MDR modulation is incomplete. In this article, we examine the electrical properties of the human leukemic cells (K562) and its MDR counterpart (K562AR) using dielectrophoresis and flow cytometry (with a membrane potential sensitive dye, DIOC5), both before and after treatment with X...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
In chemotherapy, cancer cells may show resistance to a wide range of anticancer drugs, a phenomenon ...
AbstractIn cancer, multidrug resistance (MDR) is the simultaneous resistance of tumor cells to diffe...
In cancer, multidrug resistance (MDR) is the simultaneous resistance of tumor cells to different nat...
The development of resistance to antineoplastic drugs is a major obstacle in the treatment of cancer...
Backgroud: The effectiveness of chemotherapy is limited by the emergence of multidrug resistance (MD...
Chemotherapy remains the mainstay in the treatment and management of many cancers. However, this tre...
Multidrug resistance (MDR) describes the phenomenon whereby cancer cellsexposed to a single cytotoxi...
Chemotherapy remains the mainstay in the treatment and management of many cancers. However, this tre...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
In chemotherapy, cancer cells may show resistance to a wide range of anticancer drugs, a phenomenon ...
AbstractIn cancer, multidrug resistance (MDR) is the simultaneous resistance of tumor cells to diffe...
In cancer, multidrug resistance (MDR) is the simultaneous resistance of tumor cells to different nat...
The development of resistance to antineoplastic drugs is a major obstacle in the treatment of cancer...
Backgroud: The effectiveness of chemotherapy is limited by the emergence of multidrug resistance (MD...
Chemotherapy remains the mainstay in the treatment and management of many cancers. However, this tre...
Multidrug resistance (MDR) describes the phenomenon whereby cancer cellsexposed to a single cytotoxi...
Chemotherapy remains the mainstay in the treatment and management of many cancers. However, this tre...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Multi-drug resistance (MDR) occurs when cancer cells become resistant to multiple chemotherapeutic d...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
Because of the similarities between the cystic fibrosis transmembrane conductance regulator (CFTR) a...
In chemotherapy, cancer cells may show resistance to a wide range of anticancer drugs, a phenomenon ...