DOIAbstract
It has been shown that self-reactive T cells can be detected in the periphery. In this issue of Immunity, Yu et al. (2015) show that clonal deletion prunes the T cell repertoire but does not eliminate self-reactive T cell clones
It has been shown that self-reactive T cells can be detected in the periphery. In this issue of Immunity, Yu et al. (2015) show that clonal deletion prunes the T cell repertoire but does not eliminate self-reactive T cell clones
SummaryHow self-peptides displayed in the thymus contribute to the development of immunocompetent an...
Selection in the thymus restricted by MHC and self-peptide shapes the diverse reactivities of the T-...
SummaryIt has long been thought that clonal deletion efficiently removes almost all self-specific T ...
It has been shown that self-reactive T cells can be detected in the periphery. In this issue of Immu...
AbstractHow negative selection shapes a polyclonal population of self-reactive T cells has been diff...
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8(+) T cells...
SummaryWhereas high-avidity recognition of peptide-MHC complexes by developing T cells in the thymus...
SummaryThe degree of T cell self-reactivity considered dangerous by the immune system, thereby requi...
SummaryDeveloping T cells express diverse antigen receptors whose specificities are not prematched t...
AbstractTo understand how thymic selection gives rise to T cells that are capable of major histocomp...
T cells are the central mediators of adaptive immunity and provide diverse receptors to recognize pa...
The peripheral T cell repertoire is sculpted from prototypic T cells in the thymus bearing randomly ...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
To be effective in recognizing a wide variety of pathogens, the adaptive immune system must generate...
SummaryHow self-peptides displayed in the thymus contribute to the development of immunocompetent an...
Selection in the thymus restricted by MHC and self-peptide shapes the diverse reactivities of the T-...
SummaryIt has long been thought that clonal deletion efficiently removes almost all self-specific T ...
It has been shown that self-reactive T cells can be detected in the periphery. In this issue of Immu...
AbstractHow negative selection shapes a polyclonal population of self-reactive T cells has been diff...
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8(+) T cells...
SummaryWhereas high-avidity recognition of peptide-MHC complexes by developing T cells in the thymus...
SummaryThe degree of T cell self-reactivity considered dangerous by the immune system, thereby requi...
SummaryDeveloping T cells express diverse antigen receptors whose specificities are not prematched t...
AbstractTo understand how thymic selection gives rise to T cells that are capable of major histocomp...
T cells are the central mediators of adaptive immunity and provide diverse receptors to recognize pa...
The peripheral T cell repertoire is sculpted from prototypic T cells in the thymus bearing randomly ...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
To be effective in recognizing a wide variety of pathogens, the adaptive immune system must generate...
SummaryHow self-peptides displayed in the thymus contribute to the development of immunocompetent an...
Selection in the thymus restricted by MHC and self-peptide shapes the diverse reactivities of the T-...
SummaryIt has long been thought that clonal deletion efficiently removes almost all self-specific T ...
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