V(D)J recombination of antigen receptor gene segments in B and T cells is mediated by the lymphoid-specific proteins RAG1 and RAG2. Now, Ji et al. (2010) demonstrate how RAG1 and RAG2 use DNA sequence specificity and modified histones within chromatin to target specific loci for V(D)J recombination at different stages of lymphoid development
Genome-wide analysis of thymic lymphomas from Tp53(-/-) mice with wild-type or C-terminally truncate...
AbstractDuring V(D)J recombination, RAG1 and RAG2 cleave DNA adjacent to highly conserved recombinat...
The RAG recombinase is a domesticated transposable element co-opted in jawed vertebrates to drive th...
V(D)J recombination of antigen receptor gene segments in B and T cells is mediated by the lymphoid-s...
In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H...
SummaryV(D)J recombination is a tightly controlled process of somatic recombination whose regulation...
V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are r...
AbstractThe RAG1 and RAG2 proteins are known to initiate V(D)J recombination by making a double-stra...
SummaryV(D)J gene segment recombination is linked to the cell cycle by the periodic phosphorylation ...
SummaryThe RAG1 endonuclease, together with its cofactor RAG2, is essential for V(D)J recombination ...
AbstractV(D)J recombination assembles functional immunoglobulin and T cell receptor genes from indiv...
SummaryV(D)J recombination is initiated by the recombination activating gene (RAG) proteins RAG-1 an...
RAG1 protein is essential for the activation of V(D)J recombination in developing lymphocytes (V, va...
SummaryV(D)J recombination is initiated by a specialized transposase consisting of the subunits RAG-...
Phagocytosis is a complex process that involves multiple cellular functions. In this issue of Immuni...
Genome-wide analysis of thymic lymphomas from Tp53(-/-) mice with wild-type or C-terminally truncate...
AbstractDuring V(D)J recombination, RAG1 and RAG2 cleave DNA adjacent to highly conserved recombinat...
The RAG recombinase is a domesticated transposable element co-opted in jawed vertebrates to drive th...
V(D)J recombination of antigen receptor gene segments in B and T cells is mediated by the lymphoid-s...
In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H...
SummaryV(D)J recombination is a tightly controlled process of somatic recombination whose regulation...
V(D)J recombination substrate choice is regulated to ensure that the appropriate gene segments are r...
AbstractThe RAG1 and RAG2 proteins are known to initiate V(D)J recombination by making a double-stra...
SummaryV(D)J gene segment recombination is linked to the cell cycle by the periodic phosphorylation ...
SummaryThe RAG1 endonuclease, together with its cofactor RAG2, is essential for V(D)J recombination ...
AbstractV(D)J recombination assembles functional immunoglobulin and T cell receptor genes from indiv...
SummaryV(D)J recombination is initiated by the recombination activating gene (RAG) proteins RAG-1 an...
RAG1 protein is essential for the activation of V(D)J recombination in developing lymphocytes (V, va...
SummaryV(D)J recombination is initiated by a specialized transposase consisting of the subunits RAG-...
Phagocytosis is a complex process that involves multiple cellular functions. In this issue of Immuni...
Genome-wide analysis of thymic lymphomas from Tp53(-/-) mice with wild-type or C-terminally truncate...
AbstractDuring V(D)J recombination, RAG1 and RAG2 cleave DNA adjacent to highly conserved recombinat...
The RAG recombinase is a domesticated transposable element co-opted in jawed vertebrates to drive th...
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