Synthesis of Sphere-like Nanoparticles of Hydroxyapatite

AbstractHydroxyapatite due to its excellent biocompatibility, bioactivity and osteoconductivity is widely used in orthopedic, dental, and maxillofacial applications for bone reconstruction. Nanoparticles of hydroxyapatite, which are prepared synthetically, have chemical and structural similarity with nature hydroxyapatite of bones and teeth. Sphere-like nanoparticles of hydroxyapatite were synthesized by wet chemical precipitation method under atmospheric pressure, using calcium nitrate and diammonium phosphate as reactants and ammonia was chosen as pH adjusting agent. The crystal morphology and particle size were analyzed by atomic force microscopy and X-ray disc centrifuge system. Composition and chemical structure were identified by X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetric analysis