Cyclo-oxygenase-2 Inhibitors and Peripheral Thrombosis – A Case Report Demonstrating a Possible Adverse Effect

AbstractCyclo-oxygenase-2 inhibitors are thought to be associated with an increased risk of cardiovascular events as a result of alteration in hemostasis. We report the case of a 39-year-old patient with minimal risk factors for cardiovascular disease who was prescribed a cyclo-oxygenase-2 inhibitor. He presented with symptoms of distal vessel thrombosis which was confirmed with angiography; this provides further evidence of the possible association of cyclo-oxygenase-2 inhibitors and thrombus formation