Psoriasis induced by Interferon alfa-2a and ribavirin in a patient followed for hepatitis C

Amraoui, N.
Gallouj, S.
Oubelkacem, N.
Bono, W.
Mernissi, F.

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Publication date

July 2015

DOI

10.1016/j.jdds.2015.01.002

Publisher

The Authors. Production and hosting by Elsevier B.V.

ISSN

2352-2410

Abstract

AbstractIn patients suffering from chronic hepatitis C, Interferon (INF) associated with ribavirin therapy can induce various side effects involving the skin. Our case describes the clinical course of a patient with chronic hepatitis C treated with pegylated α2 INF plus ribavirin. After 6weeks of therapy he developed psoriasis. However, given the progressive improvement of his transaminase levels and viral load decrease, we continued the protocol of the treatment and we started topical calcipotriol/betamethasone dipropionate ointment for psoriasic lesions. After this, the psoriasis improved in a slow but comprehensive manner. This paper suggests that physicians should keep in mind the possibility of the onset of psoriasis as a side effect o...