The unfolded protein response (UPRmt) rebalances mitochondrial protein homeostasis upon proteotoxic perturbations. Haynes et al. (2010) show that this retrograde stress signal is based on efflux of peptides derived from damaged proteins from the mitochondrial matrix to the cytosol; this initiates downstream protective responses in the nucleus to restore cellular balance
Mitochondria exist as compartmentalized units, surrounded by a selectively permeable double membrane...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Pathology, 2017.Mi...
The ability to respond to various intracellular and/or extracellular stresses allows the organism to...
The unfolded protein response (UPRmt) rebalances mitochondrial protein homeostasis upon proteotoxic ...
Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensuri...
Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria ...
Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensur...
The induction of the mitochondrial unfolded protein response (UPRmt) results in increased transcript...
Abstract: Mitochondrial unfolded protein response is a form of retrograde signaling that contributes...
SummaryThe cellular response to unfolded and misfolded proteins in the mitochondrial matrix is poorl...
Mitochondria, the main site of cellular energy harvesting, are derived from proteobacteria that evol...
SummaryStress-regulated signaling pathways protect mitochondrial proteostasis and function from path...
Mitochondrial and cytosolic proteostasis are of central relevance for cellular stress resistance and...
AbstractMitochondria are compartmentalized organelles essential for numerous cellular functions incl...
Mitochondria–nucleus (mitonuclear) retrograde signaling via nuclear import of otherwise mitoch...
Mitochondria exist as compartmentalized units, surrounded by a selectively permeable double membrane...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Pathology, 2017.Mi...
The ability to respond to various intracellular and/or extracellular stresses allows the organism to...
The unfolded protein response (UPRmt) rebalances mitochondrial protein homeostasis upon proteotoxic ...
Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensuri...
Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria ...
Mitochondrial unfolded protein response is a form of retrograde signaling that contributes to ensur...
The induction of the mitochondrial unfolded protein response (UPRmt) results in increased transcript...
Abstract: Mitochondrial unfolded protein response is a form of retrograde signaling that contributes...
SummaryThe cellular response to unfolded and misfolded proteins in the mitochondrial matrix is poorl...
Mitochondria, the main site of cellular energy harvesting, are derived from proteobacteria that evol...
SummaryStress-regulated signaling pathways protect mitochondrial proteostasis and function from path...
Mitochondrial and cytosolic proteostasis are of central relevance for cellular stress resistance and...
AbstractMitochondria are compartmentalized organelles essential for numerous cellular functions incl...
Mitochondria–nucleus (mitonuclear) retrograde signaling via nuclear import of otherwise mitoch...
Mitochondria exist as compartmentalized units, surrounded by a selectively permeable double membrane...
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Pathology, 2017.Mi...
The ability to respond to various intracellular and/or extracellular stresses allows the organism to...
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