While the microtubule-binding capacity of the protein tau has been known for many years, new functions of tau in signaling and cytoskeletal organization have recently emerged. In this review, we highlight these functions and the potential roles of tau in neurodegenerative disease. We also discuss the therapeutic potential of drugs targeting various aspects of tau biology
AbstractMany proteins that are implicated in human disease are posttranslationally modified. This in...
Tau protein is a neuronal microtubule (MT) associated protein whose aggregation is one of the hallma...
AbstractThe microtubule-associated protein tau, abundant in neurons, has gained notoriety due to the...
While the microtubule-binding capacity of the protein tau has been known for many years, new functio...
Tau is well established as a microtubule-associated protein in neurons. However, under pathological ...
Tau is a brain microtubule-associated protein that directly binds to a microtubule and dynamically r...
Since the discovery of the microtubule-associated protein Tau (MAPT) over 40 years ago, most studies...
AbstractTau becomes characteristically altered both functionally and structurally in several neurode...
Tau is a brain microtubule-associated protein that directly binds to a microtubule and dynamically r...
AbstractIntracellular assembly of microtubule-associated protein tau into filamentous inclusions is ...
Tau, one of the major microtubule-associated proteins, modulates the dynamic properties of microtubu...
The abnormal deposition of proteins in and around neurons is a common pathological feature of many n...
Tau is a neuronal microtubule associated protein whose main biological functions are to promote micr...
Tau is a key dynamic regulator of microtubules in neurons. Tau-microtubule binding contributes to ax...
The microtubule-associated protein 'tau' is primarily expressed within axons in the central nervous ...
AbstractMany proteins that are implicated in human disease are posttranslationally modified. This in...
Tau protein is a neuronal microtubule (MT) associated protein whose aggregation is one of the hallma...
AbstractThe microtubule-associated protein tau, abundant in neurons, has gained notoriety due to the...
While the microtubule-binding capacity of the protein tau has been known for many years, new functio...
Tau is well established as a microtubule-associated protein in neurons. However, under pathological ...
Tau is a brain microtubule-associated protein that directly binds to a microtubule and dynamically r...
Since the discovery of the microtubule-associated protein Tau (MAPT) over 40 years ago, most studies...
AbstractTau becomes characteristically altered both functionally and structurally in several neurode...
Tau is a brain microtubule-associated protein that directly binds to a microtubule and dynamically r...
AbstractIntracellular assembly of microtubule-associated protein tau into filamentous inclusions is ...
Tau, one of the major microtubule-associated proteins, modulates the dynamic properties of microtubu...
The abnormal deposition of proteins in and around neurons is a common pathological feature of many n...
Tau is a neuronal microtubule associated protein whose main biological functions are to promote micr...
Tau is a key dynamic regulator of microtubules in neurons. Tau-microtubule binding contributes to ax...
The microtubule-associated protein 'tau' is primarily expressed within axons in the central nervous ...
AbstractMany proteins that are implicated in human disease are posttranslationally modified. This in...
Tau protein is a neuronal microtubule (MT) associated protein whose aggregation is one of the hallma...
AbstractThe microtubule-associated protein tau, abundant in neurons, has gained notoriety due to the...
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