An oligofluorene truxene based distributed feedback laser for biosensing applications
- Haughey, Anne-Marie
- Guilhabert, Benoit
- L Kanibolotsky, Alexander
- J Skabara, Peter
- D Dawson, Martin
- A Burley, Glenn
- Laurand, Nicolas
Publication date
April 2014
DOI Publisher
The Authors. Published by Elsevier B.V.Abstract
AbstractThe first example of an all-organic oligofluorene truxene based distributed feedback laser for the detection of a specific protein–small molecule interaction is reported. The protein avidin was detected down to 1μgmL−1 using our biotin-labelled biosensor platform. This interaction was both selective and reversible when biotin was replaced with desthiobiotin. Avidin detection was not perturbed by Bovine Serum Albumin up to 50,000μgmL−1. Our biosensor offers a new detection platform that is both highly sensitive, modular and potentially re-usable
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