In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable molecule acrylamide-azobenzene-quaternary ammonium (AAQ) to the eyes of mice with end-stage retinal degeneration. Results show that, with the appropriate illumination, AAQ restores light sensitivity and visual behavior
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Optogenetic strategies to restore vision in patients blind from end-stage retinal degenerations aim ...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable mole...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blindin...
This dissertation addresses two non-genetic therapeutic approaches for treating inherited retinal di...
(RGCs). Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoida...
Photopharmacology has yielded compounds that have potential to restore impaired visual responses res...
Most inherited forms of human blindness are caused by mutations that lead to photoreceptor cell deat...
AbstractPhotoswitches are traditional pharmacologic agonists, antagonists, or channel blockers that ...
SummaryOuter retinal degeneration is the leading cause of blindness in the developed world. A new st...
The eye often leads the way in the development of novel strategies for treating neurodegenerative di...
Channelrhodopsin-2 (ChR2), a directly light-gated cation channel from the green alga Chlamydomonas r...
Retinitis pigmentosa results in blindness due to degeneration of photoreceptors, but spares other re...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Optogenetic strategies to restore vision in patients blind from end-stage retinal degenerations aim ...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable mole...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blindin...
This dissertation addresses two non-genetic therapeutic approaches for treating inherited retinal di...
(RGCs). Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoida...
Photopharmacology has yielded compounds that have potential to restore impaired visual responses res...
Most inherited forms of human blindness are caused by mutations that lead to photoreceptor cell deat...
AbstractPhotoswitches are traditional pharmacologic agonists, antagonists, or channel blockers that ...
SummaryOuter retinal degeneration is the leading cause of blindness in the developed world. A new st...
The eye often leads the way in the development of novel strategies for treating neurodegenerative di...
Channelrhodopsin-2 (ChR2), a directly light-gated cation channel from the green alga Chlamydomonas r...
Retinitis pigmentosa results in blindness due to degeneration of photoreceptors, but spares other re...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Optogenetic strategies to restore vision in patients blind from end-stage retinal degenerations aim ...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
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