AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene or the metal chelator clioquinol prevent oxidative damage and MPTP toxicity in mice. This raises the issue of specific iron chelators or clioquinol for control of oxidative damage in Parkinson's, Alzheimer's, and other neurodegenerative diseases, but not without safety concerns
Dysregulation of iron metabolism has been observed in patients with neurodegenerative diseases (NDs)...
Artículo de publicación ISIAbundant evidence indicates that iron accumulation, oxidative damage and ...
Over the decades, various studies have established an association between accumulation of iron and b...
AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene o...
AbstractStudies on postmortem brains from Parkinson's patients reveal elevated iron in the substanti...
Many evidences indicate that oxidative stress plays a significant role in a variety of human disease...
Abstract. Brain iron is an essential nutrient for multiple functions, including gene expression, DNA...
© 2015 Aguirre et al. This is an open access article distributed under the terms of the Creative Com...
Brain iron accumulation has been associated with inciting the generation of oxidative stress in a ho...
Disturbance of cerebral iron regulation is almost universal in neurodegenerative disorders. There is...
The homeostasis of transition metal ions is central to many life processes, but the alterations in F...
Focal iron accumulation associated with brain iron dyshomeostasis is a pathological hallmark of vari...
<p>Excessive amounts of labile metals such as iron, zinc, and copper have been found in the brains o...
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerati...
International audienceIron accumulation has been observed in mouse models and in both sporadic and f...
Dysregulation of iron metabolism has been observed in patients with neurodegenerative diseases (NDs)...
Artículo de publicación ISIAbundant evidence indicates that iron accumulation, oxidative damage and ...
Over the decades, various studies have established an association between accumulation of iron and b...
AbstractIn this issue of Neuron, Kaur et al. demonstrate that iron chelation by ferritin transgene o...
AbstractStudies on postmortem brains from Parkinson's patients reveal elevated iron in the substanti...
Many evidences indicate that oxidative stress plays a significant role in a variety of human disease...
Abstract. Brain iron is an essential nutrient for multiple functions, including gene expression, DNA...
© 2015 Aguirre et al. This is an open access article distributed under the terms of the Creative Com...
Brain iron accumulation has been associated with inciting the generation of oxidative stress in a ho...
Disturbance of cerebral iron regulation is almost universal in neurodegenerative disorders. There is...
The homeostasis of transition metal ions is central to many life processes, but the alterations in F...
Focal iron accumulation associated with brain iron dyshomeostasis is a pathological hallmark of vari...
<p>Excessive amounts of labile metals such as iron, zinc, and copper have been found in the brains o...
Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerati...
International audienceIron accumulation has been observed in mouse models and in both sporadic and f...
Dysregulation of iron metabolism has been observed in patients with neurodegenerative diseases (NDs)...
Artículo de publicación ISIAbundant evidence indicates that iron accumulation, oxidative damage and ...
Over the decades, various studies have established an association between accumulation of iron and b...
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