A New Notch for Lung Stem Cells

Homeostasis and repair of different lung compartments require the selective activation of specific progenitor/stem cells and their regulated differentiation to yield cell types that fulfill specialized regional functions. In this issue of Cell Stem Cell, Pardo-Saganta et al. (2015) identify Notch signaling as a determinant of basal cell heterogeneity and fate decisions in pseudostratified airways