Possible bioactive conformations of α-melanotropin
- Nikiforovich, G.V.
- Rozenblit, S.A.
- Shenderovich, M.D.
- Chipens, G.I.
Publication date
May 1984
DOI Publisher
Published by Elsevier B.V. ISSN
0014-5793 Citation count (estimate)
10Abstract
AbstractBy comparing the results of energy calculation for α-MSH and its semirigid analogues , , and , a detailed description of two possible bioactive conformations for the ‘specific’ central site of α-MSH6–9 is proposed representing variants of chain-reversal structure. A possible explanation of the rise in melanotropic activity of the latter two semirigid analogues is presented
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