Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9)
- De Sousa, P.A.
- Tye, B.J.
- Bruce, K.
- Dand, P.
- Russell, G.
- Collins, D.M.
- Greenshields, A.
- McDonald, K.
- Bradburn, H.
- Canham, M.A.
- Kunath, T.
- Downie, J.M.
- Bateman, M.
- Courtney, A.
Publication date
July 2016
DOI Publisher
The Authors. Published by Elsevier B.V. ISSN
1873-5061Abstract
AbstractThe human embryonic stem cell line RCe013-A (RC-9) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a failed to fertilise oocyte voluntarily donated as unsuitable and surplus to fertility requirements following informed consent. RCe013-A (RC-9) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro and in vivo. It has a normal 46XY male karyotype and microsatellite PCR identity, HLA and blood group typing data are available
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