0390: Cardiac involvement in systemic lupus erythematosus: about 80 cases

IntroductionSystemic lupus erythematosus (SLE) is an autoimmune disease with a large clinical polymorphism. Many factors: genetic, endocrine, immunological and environment contribute to disease onset. SLE is characterized by the involvement of multiple viscera, particularly the kidney, the heart and the skin. Cardiac manifestations are relatively common and can involve life-threatening.Materials and methodsThis is a retrospective descriptive study out of ten years, on the records of patients admitted in our department of internal medicine for LES (final diagnosis according to the criteria of the American Rheumatology Association: ACR). We studied the case with cardiac events.ResultsIn a series of 80 cases of SLE patients, cardiac involvement was retained in 70% of patients. It was dominated by pericarditis in 52% of cases and it was symptomatic in 30% of them. Ultrasound noted endocarditis in 44% of cases with lesions of the mitral valve in 74% of cases. Myocarditis with left ventricular failure was observed in six patients. These events had occurred at the beginning of the disease in 60% of patients. Indeed, patients had dyspnea in 30% of cases, chest pain in 25% of cases. At ECG, a micro-voltage was noted in 40% of cases (pericarditis). Echocardiography has contributed to the diagnosis of pericarditis, myocarditis and endocarditis. The treatment was the strengthening of corticosteroids.ConclusionCardiac manifestations of SLE are severe and asymptomatic in most cases. Their research must be systematic in order to treat earlier. Ultrasound appears to be the first-line examination in the detection of cardiac involvement in SLE. The prognosis remains severe coronary insufficiency and rhythm disorders