SummarySeparating mitotic error correction, chromosome biorientation and the spindle assembly checkpoint (SAC) is complicated by their interconnected relationships. New research finds that Aurora B kinase, which drives error correction and promotes biorientation, also directly regulates the SAC
AbstractHow kinetochores correct improper microtubule attachments and regulate the spindle checkpoin...
The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubu...
SummaryThe spindle checkpoint is a surveillance system acting in mitosis to delay anaphase onset unt...
Accurate chromosome segregation is dependent on the spindle assembly checkpoint (SAC). In current mo...
The spindle checkpoint is a mitotic surveillance mechanism that delays anaphase until all sister chr...
SummaryMaintenance of chromosomal stability relies on coordination between various processes that ar...
Mitosis is controlled by multiple kinases that drive cell cycle progression and prevent chromosome m...
International audienceDuring the prometaphase stage of mitosis, the cell builds a bipolar spindle of...
Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack of Auro...
Faithful separation of chromosomes prior to cell division at mitosis is a highly regulated process. ...
AbstractWe investigated why treatment of cells with dual aurora A and B kinase inhibitors produces p...
Aurora B and the spindle assembly checkpoint (SAC) collaborate to ensure the proper biorientation of...
SummaryMaintenance of genome stability during cell division depends on establishing correct attachme...
Trabajo presentado en los Cell and Developmental Biology Programme Seminar. Centre de Regulació Genò...
Ever, even when all kinetochores are unattached the spindle assembly checkpoint is not capable of in...
AbstractHow kinetochores correct improper microtubule attachments and regulate the spindle checkpoin...
The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubu...
SummaryThe spindle checkpoint is a surveillance system acting in mitosis to delay anaphase onset unt...
Accurate chromosome segregation is dependent on the spindle assembly checkpoint (SAC). In current mo...
The spindle checkpoint is a mitotic surveillance mechanism that delays anaphase until all sister chr...
SummaryMaintenance of chromosomal stability relies on coordination between various processes that ar...
Mitosis is controlled by multiple kinases that drive cell cycle progression and prevent chromosome m...
International audienceDuring the prometaphase stage of mitosis, the cell builds a bipolar spindle of...
Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack of Auro...
Faithful separation of chromosomes prior to cell division at mitosis is a highly regulated process. ...
AbstractWe investigated why treatment of cells with dual aurora A and B kinase inhibitors produces p...
Aurora B and the spindle assembly checkpoint (SAC) collaborate to ensure the proper biorientation of...
SummaryMaintenance of genome stability during cell division depends on establishing correct attachme...
Trabajo presentado en los Cell and Developmental Biology Programme Seminar. Centre de Regulació Genò...
Ever, even when all kinetochores are unattached the spindle assembly checkpoint is not capable of in...
AbstractHow kinetochores correct improper microtubule attachments and regulate the spindle checkpoin...
The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubu...
SummaryThe spindle checkpoint is a surveillance system acting in mitosis to delay anaphase onset unt...