Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of type 2 diabetes. Several targets to account for its therapeutic effects have been proposed, but a recent paper suggests a novel mechanism in which it antagonizes the cyclic AMP-dependent effects of glucagon on hepatic glucose production
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
The extract from the plant Galega officinalis containing the guanidine derivative galegin has been u...
The extract from the plant Galega officinalis containing the guanidine derivative galegin has been u...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
A recent Cell paper by He et al. (2009) shows how metformin circumvents a block between insulin and ...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
The extract from the plant Galega officinalis containing the guanidine derivative galegin has been u...
The extract from the plant Galega officinalis containing the guanidine derivative galegin has been u...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
A recent Cell paper by He et al. (2009) shows how metformin circumvents a block between insulin and ...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
8 pagesInternational audienceConsiderable efforts have been made since the 1950s to better understan...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...