It was shown previously that a significant fraction of the myosin crossbridges is attached to actin in the skinned rabbit psoas fibers under relaxed conditions at low ionic strength and low temperature (Brenner, B., M. Schoenberg, J. M. Chalovich, L. E. Greene, and E. Eisenberg. 1982. Proc. Natl. Acad. Sci. USA. 79:7288–7291; Brenner, B., L. C. Lu, and R. J. Podolsky. 1984. Biophys. J. 46:299–306). In the present work, the structure of the attached crossbridges in the relaxed state between ionic strengths of 20 and 100 mM, as compared with that in the rigor state, is further examined by equatorial x-ray diffraction. Mass distributions projected along the fiber axis are reconstructed based on the first five equatorial reflections such that t...
Previously we showed that stiffness of relaxed fibers and active force generated in single skinned f...
AbstractThe effects of the applied stretch and MgADP binding on the structure of the actomyosin cros...
Using the intensity of the outer part of the second actin layer line as an indicator of thin filamen...
It was shown previously that a significant fraction of the myosin crossbridges is attached to actin ...
X-ray diffraction patterns were obtained from skinned rabbit psoas muscle under relaxing and rigor c...
AbstractIt is well established that in a skeletal muscle under relaxing conditions, cross-bridges ex...
In the presence of ATP and absence of Ca2+, muscle crossbridges have either MgATP or MgADP.Pi bound ...
AbstractA model of cross-bridges binding to actin in the weak binding A·M·ATP state is presented. Th...
Ultra-rapid freezing and electron microscopy were used to directly observe structural details of fro...
The dynamic characteristics of the low force myosin cross-bridges were determined in fully calcium-a...
AbstractTo study possible structural changes in weak cross-bridge attachment to actin upon activatio...
AbstractElectron microscopy has shown that cross-bridges (CBs) are formed at the target zone that is...
We find that at 6 degrees C in the presence of 4 mM MgPPi, at low or moderate ionic strength, skinne...
To assess the significance of the NH2-terminus of actin for cross-bridge action in muscle, skinned f...
Using data from fast time-resolved x-ray diffraction experiments on the synchrotrons at Daresbury an...
Previously we showed that stiffness of relaxed fibers and active force generated in single skinned f...
AbstractThe effects of the applied stretch and MgADP binding on the structure of the actomyosin cros...
Using the intensity of the outer part of the second actin layer line as an indicator of thin filamen...
It was shown previously that a significant fraction of the myosin crossbridges is attached to actin ...
X-ray diffraction patterns were obtained from skinned rabbit psoas muscle under relaxing and rigor c...
AbstractIt is well established that in a skeletal muscle under relaxing conditions, cross-bridges ex...
In the presence of ATP and absence of Ca2+, muscle crossbridges have either MgATP or MgADP.Pi bound ...
AbstractA model of cross-bridges binding to actin in the weak binding A·M·ATP state is presented. Th...
Ultra-rapid freezing and electron microscopy were used to directly observe structural details of fro...
The dynamic characteristics of the low force myosin cross-bridges were determined in fully calcium-a...
AbstractTo study possible structural changes in weak cross-bridge attachment to actin upon activatio...
AbstractElectron microscopy has shown that cross-bridges (CBs) are formed at the target zone that is...
We find that at 6 degrees C in the presence of 4 mM MgPPi, at low or moderate ionic strength, skinne...
To assess the significance of the NH2-terminus of actin for cross-bridge action in muscle, skinned f...
Using data from fast time-resolved x-ray diffraction experiments on the synchrotrons at Daresbury an...
Previously we showed that stiffness of relaxed fibers and active force generated in single skinned f...
AbstractThe effects of the applied stretch and MgADP binding on the structure of the actomyosin cros...
Using the intensity of the outer part of the second actin layer line as an indicator of thin filamen...