The origin and function of extrathymic Aire-expressing cells (eTACs) is incompletely defined. In this issue of Immunity, Gardner et al. (2013) show that eTACs are a distinct tolerogenic cell population that functionally inactivates CD4+ T cells to induce peripheral tolerance
In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracell...
The ability to distinguish self from nonself is crucial for proper immune system function, and disru...
A specialized subset of epithelial cells in the thymus “promiscuously” transcribes thousands of peri...
The origin and function of extrathymic Aire-expressing cells (eTACs) is incompletely defined. In thi...
In this issue of Immunity, Anderson et al. provide another clue to the riddle that is Aire—why do hu...
SummaryAire promotes the tolerization of thymocytes by inducing the expression of a battery of perip...
The autoimmune regulator (AIRE) is a facilitator of gene transcription found primarily in the thymus...
Auto-immune regulator (AIRE) is a transcription factor that is mainly known for its crucial role in ...
The autoimmune regulator (Aire) is essential for prevention of autoimmunity; its role is best unders...
Clonal diversity within the adaptive immune system, while endowing organisms with the ability to res...
The autoimmune regulator (Aire), a well-defined transcriptional regulator in the thymus, is also fou...
Mutations of the Autoimmune Regulator (Aire) were first identified as the cause of a multi-organ aut...
In thymic epithelial cells, the protein Aire (autoimmune regulator) induces the ectopic expression o...
Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytopla...
In this issue of Immunity, Blanchet et al. (2010) report that human immunodeficiency virus-1 inhibit...
In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracell...
The ability to distinguish self from nonself is crucial for proper immune system function, and disru...
A specialized subset of epithelial cells in the thymus “promiscuously” transcribes thousands of peri...
The origin and function of extrathymic Aire-expressing cells (eTACs) is incompletely defined. In thi...
In this issue of Immunity, Anderson et al. provide another clue to the riddle that is Aire—why do hu...
SummaryAire promotes the tolerization of thymocytes by inducing the expression of a battery of perip...
The autoimmune regulator (AIRE) is a facilitator of gene transcription found primarily in the thymus...
Auto-immune regulator (AIRE) is a transcription factor that is mainly known for its crucial role in ...
The autoimmune regulator (Aire) is essential for prevention of autoimmunity; its role is best unders...
Clonal diversity within the adaptive immune system, while endowing organisms with the ability to res...
The autoimmune regulator (Aire), a well-defined transcriptional regulator in the thymus, is also fou...
Mutations of the Autoimmune Regulator (Aire) were first identified as the cause of a multi-organ aut...
In thymic epithelial cells, the protein Aire (autoimmune regulator) induces the ectopic expression o...
Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytopla...
In this issue of Immunity, Blanchet et al. (2010) report that human immunodeficiency virus-1 inhibit...
In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracell...
The ability to distinguish self from nonself is crucial for proper immune system function, and disru...
A specialized subset of epithelial cells in the thymus “promiscuously” transcribes thousands of peri...
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