In this issue of Chemistry & Biology, Schust et al. [1] report the discovery of a small molecule (Stattic) that inhibits the binding of a high affinity phosphopeptide for the SH2 domain of Stat3. Stattic is a new tool for studying Stat3 signaling and demonstrates that the SH2 domain is not a dead target
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transc...
Molecular approaches towards Stat3 inhibition: Stat3 inhibition represents an exciting new approach ...
Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delav...
In this issue of Chemistry & Biology, Schust et al. [1] report the discovery of a small molecule (St...
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the p...
STAT3 is one of the seven family members of the STAT transcription factor family. STAT3 has become ...
SummarySignal transducers and activators of transcription (STATs) are a family of latent cytoplasmic...
Signal transducer and activator of transcription (Stat) 3 is an oncogene constitutively activated in...
Signal transducer and activator of transcription (Stat) 3 is an oncogene constitutively activated in...
© 2014 American Chemical Society. We herein report the design and synthesis of the first nanomolar b...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Signal transducers and activators of transcription (STATs) facilitate action of cytokines, growth fa...
Signal transducers and activators of transcription (STATs) facilitate action of cytokines, growth fa...
Signal transducer and activator of transcription 3 (STAT3) is a cancer-driving proto-oncoprotein tha...
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transc...
Molecular approaches towards Stat3 inhibition: Stat3 inhibition represents an exciting new approach ...
Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delav...
In this issue of Chemistry & Biology, Schust et al. [1] report the discovery of a small molecule (St...
Advances in anti-cancer drug development have vastly improved cancer treatment strategies over the p...
STAT3 is one of the seven family members of the STAT transcription factor family. STAT3 has become ...
SummarySignal transducers and activators of transcription (STATs) are a family of latent cytoplasmic...
Signal transducer and activator of transcription (Stat) 3 is an oncogene constitutively activated in...
Signal transducer and activator of transcription (Stat) 3 is an oncogene constitutively activated in...
© 2014 American Chemical Society. We herein report the design and synthesis of the first nanomolar b...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Stat-3 (Signal Transduction and Activator of Transcription) is a member of the Stat family of latent...
Signal transducers and activators of transcription (STATs) facilitate action of cytokines, growth fa...
Signal transducers and activators of transcription (STATs) facilitate action of cytokines, growth fa...
Signal transducer and activator of transcription 3 (STAT3) is a cancer-driving proto-oncoprotein tha...
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transc...
Molecular approaches towards Stat3 inhibition: Stat3 inhibition represents an exciting new approach ...
Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delav...
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