Renal effects and mesangial cell contraction induced by endothelin are mediated by PAF. The recently discovered vasoactive peptide endothelin and platelet activating factor (PAF) share similar renal effects. The purpose of the present series of experiments has been to analyze the functional relations between the effect of endothelin on renal function and glomerular and mesangial cell contraction and the production and actions of PAF in kidney. Endothelin 1 nmol/kg body wt induced a transient decrease of glomerular filtration rate (from 1.99 ± 0.17 to 0.56 ± 0.18 ml/min) and renal blood flow (from 10.8 ± 1.3 to 2.7 ± 0.3 ml/min). Endothelin also induced a marked reduction of planar cell surface area of cultured mesangial cells (30 ± 5%) and ...
Over 30,000 publications have been published about the vasoconstrictor endothelin-1, which was ident...
Endothelin (ET), a potent endothelium-derived vasoconstrictor peptide [1] contributes to the regulat...
Renal function after release of ureteral obstruction: Role of endothelin and the renal artery endoth...
Renal effects and mesangial cell contraction induced by endothelin are mediated by PAF. The recently...
Endothelin stimulates PDGF secretion in cultured human mesangial cells. Endothelin, a 17-DKa peptide...
Endothelin and eicosanoid synthesis in cultured mesangial cells. We investigated the effect of endot...
Effects of endothelin-1 on renal function in humans: Implications for physiology and pathophysiology...
Heparin inhibits endothelin-1 production in cultured rat mesangial cells. The present study was desi...
Endothelin-1 receptor antagonist: Effects on endothelin- and cyclosporine-treated mesangial cells. E...
Endothelin-1 receptor blockade prevents renal injury in experimental hypercholesterolemia.Background...
Role of endothelin as a mitogen in experimental glomerulonephritis in rats. Recent studies have reve...
The objective of this research was to determine if endothelin is a mediator of hexachloro-1,3-butadi...
The newly isolated peptide, endothelin-1 (ET-1), is a potent pressor agent that reduces GFR and the ...
Effects of endothelin on hemodynamics, prostaglandins, blood coagulation and renal function. The int...
Role of endothelin in cyclosporine-induced glomerular dysfunction. Since recent studies indicate tha...
Over 30,000 publications have been published about the vasoconstrictor endothelin-1, which was ident...
Endothelin (ET), a potent endothelium-derived vasoconstrictor peptide [1] contributes to the regulat...
Renal function after release of ureteral obstruction: Role of endothelin and the renal artery endoth...
Renal effects and mesangial cell contraction induced by endothelin are mediated by PAF. The recently...
Endothelin stimulates PDGF secretion in cultured human mesangial cells. Endothelin, a 17-DKa peptide...
Endothelin and eicosanoid synthesis in cultured mesangial cells. We investigated the effect of endot...
Effects of endothelin-1 on renal function in humans: Implications for physiology and pathophysiology...
Heparin inhibits endothelin-1 production in cultured rat mesangial cells. The present study was desi...
Endothelin-1 receptor antagonist: Effects on endothelin- and cyclosporine-treated mesangial cells. E...
Endothelin-1 receptor blockade prevents renal injury in experimental hypercholesterolemia.Background...
Role of endothelin as a mitogen in experimental glomerulonephritis in rats. Recent studies have reve...
The objective of this research was to determine if endothelin is a mediator of hexachloro-1,3-butadi...
The newly isolated peptide, endothelin-1 (ET-1), is a potent pressor agent that reduces GFR and the ...
Effects of endothelin on hemodynamics, prostaglandins, blood coagulation and renal function. The int...
Role of endothelin in cyclosporine-induced glomerular dysfunction. Since recent studies indicate tha...
Over 30,000 publications have been published about the vasoconstrictor endothelin-1, which was ident...
Endothelin (ET), a potent endothelium-derived vasoconstrictor peptide [1] contributes to the regulat...
Renal function after release of ureteral obstruction: Role of endothelin and the renal artery endoth...