Pluripotency is well defined functionally but ambiguously defined at the molecular level. In this issue of Developmental Cell, Boroviak and colleagues (2015) use a multi-species approach to differentiate between fundamental features of pluripotency in mammals and those that exhibit evolutionary plasticity
SummaryHow embryonic stem cells maintain the potential to differentiate into multiple cell lineages ...
In the mouse, naïve pluripotent stem cells (PSCs) are thought to represent the cell culture equivale...
Pluripotency is a unique developmental state that lays the foundation upon which the entire embryo i...
SummaryPluripotency is a unique developmental state that lays the foundation upon which the entire e...
Research on developmental pathways in model organisms provides key information on how to isolate, ma...
Pluripotency defines the propensity of a cell to differentiate into, and generate, all somatic, as w...
Our current understanding of how stem cells arise and transition during embryonic development has b...
Pluripotency is depicted by a self-renewing state that can competently differentiate to form the thr...
A central question in contemporary stem and developmental biology and modern medicine is how develop...
SummaryPlasticity is a well-known feature of mammalian development, and yet very little is known abo...
Plasticity is a well-known feature of mammalian development, and yet very little is known about its ...
BACKGROUND: Pluripotent stem cells have been derived from a variety of sources such as from the inne...
Pluripotent stem cells have the ability to undergo self-renewal and to give rise to all cells of the...
Pluripotency is defined as the ability to develop into all tissues of the adult organism. In vivo, p...
The recent derivation of pluripotent stem cell lines from a number of different sources, including r...
SummaryHow embryonic stem cells maintain the potential to differentiate into multiple cell lineages ...
In the mouse, naïve pluripotent stem cells (PSCs) are thought to represent the cell culture equivale...
Pluripotency is a unique developmental state that lays the foundation upon which the entire embryo i...
SummaryPluripotency is a unique developmental state that lays the foundation upon which the entire e...
Research on developmental pathways in model organisms provides key information on how to isolate, ma...
Pluripotency defines the propensity of a cell to differentiate into, and generate, all somatic, as w...
Our current understanding of how stem cells arise and transition during embryonic development has b...
Pluripotency is depicted by a self-renewing state that can competently differentiate to form the thr...
A central question in contemporary stem and developmental biology and modern medicine is how develop...
SummaryPlasticity is a well-known feature of mammalian development, and yet very little is known abo...
Plasticity is a well-known feature of mammalian development, and yet very little is known about its ...
BACKGROUND: Pluripotent stem cells have been derived from a variety of sources such as from the inne...
Pluripotent stem cells have the ability to undergo self-renewal and to give rise to all cells of the...
Pluripotency is defined as the ability to develop into all tissues of the adult organism. In vivo, p...
The recent derivation of pluripotent stem cell lines from a number of different sources, including r...
SummaryHow embryonic stem cells maintain the potential to differentiate into multiple cell lineages ...
In the mouse, naïve pluripotent stem cells (PSCs) are thought to represent the cell culture equivale...
Pluripotency is a unique developmental state that lays the foundation upon which the entire embryo i...
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