Multi-site phosphorylation of bovine kidney branched-chain 2-oxoacid dehydrogenase complex
- Cook, Kenneth G.
- Lawson, Rowena
- Yeaman, Stephen J.
Publication date
June 1983
DOI Publisher
Published by Elsevier B.V. ISSN
0014-5793 Citation count (estimate)
24Abstract
AbstractThe α-subunit of the E1 component of branched-chain 2-oxoacid dehydrogenase is phosphorylated at 3 sites by an endogenous kinase. Inactivation of the complex correlates with rapid phosphorylation of one of these sites. The similarities with the covalent regulation of pyruvate dehydrogenase complex are discussed
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