Retroviral capsids can be recognized and degraded by a host protein, Trim5α. A recent study in Nature (Pertel et al., 2011) shows that, upon sensing of the retrovirus capsid lattice, Trim5α generates free ubiquitin chains that activate the TAK1 kinase and downstream innate immune response genes
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5α is an antiviral, cytoplasmic, E3 ubiquitin (Ub) ligase that assembles on incoming retroviral ...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
International audienceTRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human i...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
The retrovirus restriction factor TRIM5α blocks post-entry infection of retroviruses in a species-sp...
AbstractTrim5α is a host antiviral protein that recognizes incoming retroviral capsids in the cytopl...
TRIM5 is a RING domain E3 ubiquitin ligase with potent antiretroviral function. TRIM5 assembles into...
Summary: TRIM5 is a RING domain E3 ubiquitin ligase with potent antiretroviral function. TRIM5 assem...
Permission to archive final published versionRestriction factors are intrinsic cellular defense prot...
Host restriction factor TRIM5 inhibits retroviral transduction in a species-specific manner by bindi...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5α is an antiviral, cytoplasmic, E3 ubiquitin (Ub) ligase that assembles on incoming retroviral ...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
International audienceTRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human i...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus ...
The retrovirus restriction factor TRIM5α blocks post-entry infection of retroviruses in a species-sp...
AbstractTrim5α is a host antiviral protein that recognizes incoming retroviral capsids in the cytopl...
TRIM5 is a RING domain E3 ubiquitin ligase with potent antiretroviral function. TRIM5 assembles into...
Summary: TRIM5 is a RING domain E3 ubiquitin ligase with potent antiretroviral function. TRIM5 assem...
Permission to archive final published versionRestriction factors are intrinsic cellular defense prot...
Host restriction factor TRIM5 inhibits retroviral transduction in a species-specific manner by bindi...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
TRIM5α is an antiviral, cytoplasmic, E3 ubiquitin (Ub) ligase that assembles on incoming retroviral ...
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and...
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