Na+-driven flagellar motor of Vibrio

AbstractBacterial flagellar motors are molecular machines powered by the electrochemical potential gradient of specific ions across the membrane. Bacteria move using rotating helical flagellar filaments. The flagellar motor is located at the base of the filament and is buried in the cytoplasmic membrane. Flagellar motors are classified into two types according to the coupling ion: namely the H+-driven motor and the Na+-driven motor. Analysis of the flagellar motor at the molecular level is far more advanced in the H+-driven motor than in the Na+-driven motor. Recently, the genes of the Na+-driven motor have been cloned from a marine bacterium of Vibrio sp. and some of the motor proteins have been purified and characterized. In this review, we summarize recent studies of the Na+-driven flagellar motor