Using Mice to Treat (Wo)men: Mining Genetic Changes in Patient Xenografts to Attack Breast Cancer
- Oesterreich, Steffi
- Brufsky, Adam M.
- Davidson, Nancy E.
Publication date
September 2013
DOI Publisher
The Authors. Published by Elsevier Inc. ISSN
2211-1247 Citation count (estimate)
3Abstract
In this issue of Cell Reports, Li et al. show that the analysis of genetic changes in patient-derived xenografts can reveal crucial details of tumor evolution, such as the emergence of functional estrogen receptor mutations in endocrine-resistant breast cancer
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