Are we detecting and operating on high risk patients in the asymptomatic carotid surgery trial?

Objective:This study aims to determine whether asymptomatic carotid surgery trial (ACST) centres have entered and can identify high risk patients using duplex.Design:Retrospective study.Materials and methods:Eighty-six vascular laboratories collaborating in ACST were studied. Equipment, operator experience, methodology and interpretation criteria were assessed. The ACST randomisation data were examined to determine whether patients believed to be at higher risk of stroke because of tight stenosis, contralateral occlusion or echolucent plaque were randomised.Results:Laboratories (92%) had colour duplex and 62% of all operators had >3 years experience in carotid evaluation. The Doppler angle used to obtain peak velocity was 30–60° in 65%, 60°; in 28% and 60–80° in 6% of laboratories. Sixty-two per cent reported diameter reduction, 27% area reduction, and 11% used both methods.One-third of 1657 randomised patients were reported to have ipsilateral echolucent plaque. Median ipsilateral stenosis was 80%, 8% had contralateral occlusion and 8.5% had bilateral >80% stenosis.Conclusions:Centres in ACST use experienced operators, high quality equipment and conscientious data recording. Variations in methods of determining carotid stenosis exist, but can be smoothed by simple data collection. Patients at higher perceived risk of stroke are being entered and with continued recruitment it should be possible to determine whether surgery improves disabling stroke-free survival