AbstractKinesin-1 is one of the motor proteins that drive intracellular transport in eukaryotes. This motor makes hundreds of 8-nm steps along a microtubule before releasing. Kinesin-1 can move at velocities of up to ∼800nm/s, which means that one turnover on average takes 10ms. Important details, however, concerning the coordination between the two motor domains have not been determined due to limitations of the techniques used. In this study, we present an approach that allows the observation of fluorescence intensity changes on individual kinesins with a time resolution far better than the duration of a single step. In our approach, the laser focus of a confocal fluorescence microscope is pointed at a microtubule and the photons emitted ...
The fluorescence-based nanoscopy methods MINFLUX and MINSTED are currently revolutionizing the field...
Recent developments in optical microscopy and nanometer tracking have greatly improved our understan...
Recent developments in optical microscopy and nanometer tracking have greatly improved our under-sta...
AbstractKinesin-1 is one of the motor proteins that drive intracellular transport in eukaryotes. Thi...
Kinesin-1 is one of the motor proteins that drive intracellular transport in eukaryotes. This motor ...
AbstractKinesin-1 motor proteins move along microtubules in repetitive steps of 8 nm at the expense ...
AbstractA fusion protein of kinesin and gelsolin binds a short actin filament which can be visualize...
AbstractThe molecular motor protein Kinesin-1 drives intracellular transport of vesicles, by binding...
Kinesin-1 motor proteins move along microtubules in repetitive steps of 8 nm at the expense of ATP. ...
AbstractMotor proteins of the kinesin family move actively along microtubules to transport cargo wit...
We report on an interferometric MINFLUX microscope that records protein movements with down to 1.7 n...
AbstractProcessive cytoskeletal motors from the myosin, kinesin, and dynein families walk on actin f...
AbstractThe hand-over-hand stepping mechanism of kinesin at low loads is inadequately understood bec...
Processive cytoskeletal motors from the myosin, kinesin, and dynein families walk on actin filaments...
AbstractUnderstanding dynamic cellular processes requires precise knowledge of the distribution, tra...
The fluorescence-based nanoscopy methods MINFLUX and MINSTED are currently revolutionizing the field...
Recent developments in optical microscopy and nanometer tracking have greatly improved our understan...
Recent developments in optical microscopy and nanometer tracking have greatly improved our under-sta...
AbstractKinesin-1 is one of the motor proteins that drive intracellular transport in eukaryotes. Thi...
Kinesin-1 is one of the motor proteins that drive intracellular transport in eukaryotes. This motor ...
AbstractKinesin-1 motor proteins move along microtubules in repetitive steps of 8 nm at the expense ...
AbstractA fusion protein of kinesin and gelsolin binds a short actin filament which can be visualize...
AbstractThe molecular motor protein Kinesin-1 drives intracellular transport of vesicles, by binding...
Kinesin-1 motor proteins move along microtubules in repetitive steps of 8 nm at the expense of ATP. ...
AbstractMotor proteins of the kinesin family move actively along microtubules to transport cargo wit...
We report on an interferometric MINFLUX microscope that records protein movements with down to 1.7 n...
AbstractProcessive cytoskeletal motors from the myosin, kinesin, and dynein families walk on actin f...
AbstractThe hand-over-hand stepping mechanism of kinesin at low loads is inadequately understood bec...
Processive cytoskeletal motors from the myosin, kinesin, and dynein families walk on actin filaments...
AbstractUnderstanding dynamic cellular processes requires precise knowledge of the distribution, tra...
The fluorescence-based nanoscopy methods MINFLUX and MINSTED are currently revolutionizing the field...
Recent developments in optical microscopy and nanometer tracking have greatly improved our understan...
Recent developments in optical microscopy and nanometer tracking have greatly improved our under-sta...