The source of TGF-β, which regulates inflammation in various disease settings, is unclear. In this issue of Immunity, Li et al. (2007) find that not only does T cell-produced TGF-β regulate Th1-cell-mediated inflammation, but it is also required for the generation of Th17 cells in vivo
A functional adaptive immune system depends on a diverse and self-tolerant population of T lymphocyt...
T helper 17 (Th17) cells are a recently discovered lineage of T lymphocytes that have been implicate...
TGF-β is widely held to be critical for the maintenance and function of regulatory T (Treg) cells an...
SummaryTGF-β1 is a regulatory cytokine with a pleiotropic role in immune responses. TGF-β1 is widely...
As Th17 cell developmental requirements continue to be studied, Gutcher et al. (2011) demonstrate in...
SummaryTGF-β1 is a regulatory cytokine that has an important role in controlling T cell differentiat...
SummaryT helper 17 (Th17) cell development is driven by cytokines including transforming growth fact...
SummaryThe role of transforming growth factor-β (TGF-β) in inhibiting T cell functions has been stud...
TGF-β is a pleiotropic cytokine that predominantly exerts inhibitory functions in the immune system....
SummaryWe describe de novo generation of IL-17-producing T cells from naive CD4 T cells, induced in ...
TGF-β is a pleiotropic cytokine that predominantly exerts inhibitory functions in the immune system....
To determine how transforming growth factor-β (TGF-β) controls T cell function, Marie et al. (2006) ...
SummaryTransforming growth factor-β (TGF-β) has been implicated in the control of differentiation an...
SummaryTransforming growth factor-β (TGF-β) and interleukin-10 (IL-10) are regulatory cytokines with...
AbstractTargeted mutation of TGFβ1 in mice demonstrated that TGFβ1 is one of the key negative regula...
A functional adaptive immune system depends on a diverse and self-tolerant population of T lymphocyt...
T helper 17 (Th17) cells are a recently discovered lineage of T lymphocytes that have been implicate...
TGF-β is widely held to be critical for the maintenance and function of regulatory T (Treg) cells an...
SummaryTGF-β1 is a regulatory cytokine with a pleiotropic role in immune responses. TGF-β1 is widely...
As Th17 cell developmental requirements continue to be studied, Gutcher et al. (2011) demonstrate in...
SummaryTGF-β1 is a regulatory cytokine that has an important role in controlling T cell differentiat...
SummaryT helper 17 (Th17) cell development is driven by cytokines including transforming growth fact...
SummaryThe role of transforming growth factor-β (TGF-β) in inhibiting T cell functions has been stud...
TGF-β is a pleiotropic cytokine that predominantly exerts inhibitory functions in the immune system....
SummaryWe describe de novo generation of IL-17-producing T cells from naive CD4 T cells, induced in ...
TGF-β is a pleiotropic cytokine that predominantly exerts inhibitory functions in the immune system....
To determine how transforming growth factor-β (TGF-β) controls T cell function, Marie et al. (2006) ...
SummaryTransforming growth factor-β (TGF-β) has been implicated in the control of differentiation an...
SummaryTransforming growth factor-β (TGF-β) and interleukin-10 (IL-10) are regulatory cytokines with...
AbstractTargeted mutation of TGFβ1 in mice demonstrated that TGFβ1 is one of the key negative regula...
A functional adaptive immune system depends on a diverse and self-tolerant population of T lymphocyt...
T helper 17 (Th17) cells are a recently discovered lineage of T lymphocytes that have been implicate...
TGF-β is widely held to be critical for the maintenance and function of regulatory T (Treg) cells an...