Ependymomas have a variable prognosis. In this issue of Cancer Cell, Pajtler and colleagues identify nine subgroups of ependymoma using DNA methylation profiles. Two subgroups, predominately pediatric, are responsible for most of the mortality, with all others having nearly 100% overall survival after 5 years
Hematopoietic homeostasis relies on the ability of hematopoietic stem cells (HSCs) to maintain both ...
The plant homeodomain 6 gene (PHF6) is frequently mutated in human T-cell acute lymphoblastic leukem...
SummaryWe analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas (MC...
We have previously shown immune gene phenotype variations between posterior fossa ependymoma subgrou...
Haematological malignancies comprise a diverse set of lymphoid and myeloid neoplasms which can arise...
Altres ajuts: the Cellex Foundation; and la Caixa Banking Foundation (LCF/PR/GN18/51140001).Altres a...
Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the c...
Ependymoma (EPN) of childhood is curable in only 50% of cases, with recurrences in the remainder tha...
Mesenchymal niche cells may drive tissue failure and malignant transformation in the hematopoietic s...
SummaryLeukemic cells disrupt normal patterns of blood cell formation, but little is understood abou...
The rapid advances in high-throughput sequencing technologies have made it more evident that epigene...
SummaryUsing a mouse model recapitulating the main features of human chronic myelogenous leukemia (C...
Ependymoma is the third commonest childhood brain tumour. Relapse is frequent, often fatal and curre...
SummaryThe genetic programs that maintain leukemia stem cell (LSC) self-renewal and oncogenic potent...
Epigenetic alterations represent a key cancer hallmark, even in hematologic malignancies (HMs) or bl...
Hematopoietic homeostasis relies on the ability of hematopoietic stem cells (HSCs) to maintain both ...
The plant homeodomain 6 gene (PHF6) is frequently mutated in human T-cell acute lymphoblastic leukem...
SummaryWe analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas (MC...
We have previously shown immune gene phenotype variations between posterior fossa ependymoma subgrou...
Haematological malignancies comprise a diverse set of lymphoid and myeloid neoplasms which can arise...
Altres ajuts: the Cellex Foundation; and la Caixa Banking Foundation (LCF/PR/GN18/51140001).Altres a...
Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the c...
Ependymoma (EPN) of childhood is curable in only 50% of cases, with recurrences in the remainder tha...
Mesenchymal niche cells may drive tissue failure and malignant transformation in the hematopoietic s...
SummaryLeukemic cells disrupt normal patterns of blood cell formation, but little is understood abou...
The rapid advances in high-throughput sequencing technologies have made it more evident that epigene...
SummaryUsing a mouse model recapitulating the main features of human chronic myelogenous leukemia (C...
Ependymoma is the third commonest childhood brain tumour. Relapse is frequent, often fatal and curre...
SummaryThe genetic programs that maintain leukemia stem cell (LSC) self-renewal and oncogenic potent...
Epigenetic alterations represent a key cancer hallmark, even in hematologic malignancies (HMs) or bl...
Hematopoietic homeostasis relies on the ability of hematopoietic stem cells (HSCs) to maintain both ...
The plant homeodomain 6 gene (PHF6) is frequently mutated in human T-cell acute lymphoblastic leukem...
SummaryWe analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas (MC...
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