AbstractBackgroundCardiopulmonary bypass induces a systemic inflammatory response that may contribute to clinical morbidity. Gaseous nitric oxide at relatively low concentrations may elicit peripheral anti-inflammatory effects in addition to a reduction of pulmonary resistances. We examined the effects of 20 ppm of inhaled nitric oxide administered for 8 hours during and after cardiopulmonary bypass.Methods and resultsTwenty-nine consecutive patients undergoing aortic valve replacement combined with aortocoronary bypass were randomly allocated to either 20 ppm of inhaled nitric oxide (n = 14) or no additional inhalatory treatment (n = 15). Blood samples for total creatine kinase, creatine kinase MB fraction, and troponin I measurements were...
AbstractFluid accumulation during cardiopulmonary bypass may be related to the production of endogen...
AbstractObjectives to investigate endogenous pulmonary nitric oxide metabolism following infrarenal ...
Cardiac surgery involving ischemic arrest and extracorporeal circulation is often associated with al...
AbstractBackgroundCardiopulmonary bypass induces a systemic inflammatory response that may contribut...
ObjectiveCardiac surgery requiring cardiopulmonary bypass and cardioplegic arrest leads to myocardia...
AbstractBackground: Cardiopulmonary bypass induces oxidative stress and a whole-body inflammatory re...
Aim. The study was designed to assess the efficiency of exogenous nitric oxide supply to the extraco...
AbstractIschemia-reperfusion damages endothelium and impairs basal production of nitric oxide. Basal...
AbstractObjective: Myocardial ischemia and reperfusion induced by cardioplegic arrest subjects the h...
AbstractObjectiveThis study tested the hypothesis that cardioplegic solution supplemented with a nit...
AbstractIncreased pulmonary vascular resistance may greatly complicate the perioperative management ...
Myocardial ischemia and reperfusion may result in endothelial dysfunction and reduced release of nit...
AbstractObjectives: P-selectin participates in the development of inflammatory disorders. Cardiopulm...
Many complications associated with heart surgery are due to the negative effects of extracorporeal c...
AbstractThis study tested the hypothesis that enhancement of blood cardioplegia with the nitric oxid...
AbstractFluid accumulation during cardiopulmonary bypass may be related to the production of endogen...
AbstractObjectives to investigate endogenous pulmonary nitric oxide metabolism following infrarenal ...
Cardiac surgery involving ischemic arrest and extracorporeal circulation is often associated with al...
AbstractBackgroundCardiopulmonary bypass induces a systemic inflammatory response that may contribut...
ObjectiveCardiac surgery requiring cardiopulmonary bypass and cardioplegic arrest leads to myocardia...
AbstractBackground: Cardiopulmonary bypass induces oxidative stress and a whole-body inflammatory re...
Aim. The study was designed to assess the efficiency of exogenous nitric oxide supply to the extraco...
AbstractIschemia-reperfusion damages endothelium and impairs basal production of nitric oxide. Basal...
AbstractObjective: Myocardial ischemia and reperfusion induced by cardioplegic arrest subjects the h...
AbstractObjectiveThis study tested the hypothesis that cardioplegic solution supplemented with a nit...
AbstractIncreased pulmonary vascular resistance may greatly complicate the perioperative management ...
Myocardial ischemia and reperfusion may result in endothelial dysfunction and reduced release of nit...
AbstractObjectives: P-selectin participates in the development of inflammatory disorders. Cardiopulm...
Many complications associated with heart surgery are due to the negative effects of extracorporeal c...
AbstractThis study tested the hypothesis that enhancement of blood cardioplegia with the nitric oxid...
AbstractFluid accumulation during cardiopulmonary bypass may be related to the production of endogen...
AbstractObjectives to investigate endogenous pulmonary nitric oxide metabolism following infrarenal ...
Cardiac surgery involving ischemic arrest and extracorporeal circulation is often associated with al...