Acute kidney injury in HIV-infected children: comparison of patients according to the use of highly active antiretroviral therapy
- Soares, Douglas de Sousa
- Cavalcante, Malena Gadelha
- Ribeiro, Samille Maria Vasconcelos
- Leitão, Rayana Café
- Vieira, Ana Patrícia Freitas
- Pires Neto, Roberto da Justa
- Silva Junior, Geraldo Bezerra da
- Daher, Elizabeth de Francesco
DOIAbstract
AbstractObjectiveTo assess clinical and laboratory data, and acute kidney injury (AKI) in HIV-infected children using and not using highly active antiretroviral therapy (HAART) prior to admission.MethodsA retrospective study was conducted with HIV-infected pediatric patients (<16 years). Children who were using and not using HAART prior to admission were compared.ResultsSixty-three patients were included. Mean age was 5.3±4.27 years; 55.6% were females. AKI was observed in 33 (52.3%) children. Patients on HAART presented lower levels of potassium (3.9±0.8 vs. 4.5±0.7mEq/L, p=0.019) and bicarbonate (19.1±4.9 vs. 23.5±2.2mEq/L, p=0.013) and had a higher estimated glomerular filtration rate (102.2±36.7 vs. 77.0±32.8mL/min/1.73m2, p=0.011) than...
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