Polycarpol in Unonopsis, Bocageopsis and Onychopetalum Amazonian species: chemosystematical implications and antimicrobial evaluation

Silva, Felipe M.A. da
Lima, Bruna R. de
Soares, Elzalina R.
Almeida, Richardson A. de
Silva Filho, Francinaldo A. da
Corrêa, Wallace R.
Salvador, Marcos J.
Souza, Antonia Q.L. de
Koolen, Hector H.F.
Souza, Afonso D.L. de
Pinheiro, Maria L.B.

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Publication date

February 2015

DOI

10.1016/j.bjp.2015.01.003

Publisher

Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda.

Abstract

AbstractPolycarpol, a recurrent lanostane-type triterpene in Annonaceae family, was confirmed by thin layer chromatography and mass spectrometry analysis in the aerial parts (twigs and trunk barks) of Unonopsis duckei R.E. Fr., U. floribunda Diels, U. rufescens (Baill.) R.E. Fr., U. stipitata Diels, Onychopetalum amazonicum R.E. Fr. and Bocageopsis pleiosperma Maas. Its chemotaxonomic significance was discussed for these three genera, as well for the Annonaceae family. In addition, the antimicrobial activity against several strains of microorganisms was evaluated for the first time for this compound, being observed significant antibacterial activity against Staphylococcus aureus (ATCC 6538), Staphylococcus epidermidis (ATCC 1228) and Escher...