Changes in transcription factor binding sequences result in correlated changes in chromatin composition locally and at sites hundreds of kilobases away. New studies demonstrate that this concordance is mediated via spatial chromatin interactions that constitute regulatory modules of the human genome
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryot...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
SummaryChromatin interactions play important roles in transcription regulation. To better understand...
BACKGROUND: The number of reported examples of chromatin architecture alterations involved in the re...
SummaryChromatin state variation at gene regulatory elements is abundant across individuals, yet we ...
BACKGROUND: The number of reported examples of chromatin architecture alterations involved in the re...
The majority of disease-associated variants lie outside protein-coding regions, suggesting a link be...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
SummaryHigher-order chromosomal organization for transcription regulation is poorly understood in eu...
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryot...
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryot...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
Changes in transcription factor binding sequences result in correlated changes in chromatin composit...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
SummaryChromatin interactions play important roles in transcription regulation. To better understand...
BACKGROUND: The number of reported examples of chromatin architecture alterations involved in the re...
SummaryChromatin state variation at gene regulatory elements is abundant across individuals, yet we ...
BACKGROUND: The number of reported examples of chromatin architecture alterations involved in the re...
The majority of disease-associated variants lie outside protein-coding regions, suggesting a link be...
SummaryDeciphering the impact of genetic variants on gene regulation is fundamental to understanding...
SummaryHigher-order chromosomal organization for transcription regulation is poorly understood in eu...
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryot...
Higher-order chromosomal organization for transcription regulation is poorly understood in eukaryot...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
Every cell in the human body contains the identical hereditary information, encoded in the DNA. The ...
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