Pyrimidine alkaloids from Eudistoma vannamei
- Takeara, Renata
- Basso, Thiago Olitta
- Jimenez, Paula Christine
- Costa-Lotufo, Letícia Veras
- Lopes, Norberto Peporine
- Lopes, João Luis Callegari
Publication date
December 2015
DOI Publisher
Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda. ISSN
0102-695X Citation count (estimate)
1Abstract
AbstractMethanolic extracts of the Brazilian endemic ascidian Eudistoma vannamei have been extensively studied for their cytotoxic activity against several human cancer cell lines. Previous work reported the occurrence of purine derivatives and staurosporine alkaloids as the major nitrogen-containing compounds. In this study, we report the occurrence of three pyrimidine alkaloids in addition to cholesterol, sitosterol and stigmasterol
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