XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth. In this issue of Cell, Cubillos-Ruiz et al. demonstrate that XBP1 in tumor-infiltrating dendritic cells blunts anti-tumor immunity. These findings further imply XBP1 as a relevant target for cancer therapy
Metabolic, infectious and tumor cell-intrinsic noxae can all evoke the endoplasmic reticulum (ER) st...
Unresolved endoplasmic reticulum (ER) stress in the epithelium can provoke intestinal inflammation. ...
Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting tumor progress...
XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth....
XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth....
SummaryDendritic cells (DCs) are required to initiate and sustain T cell-dependent anti-cancer immun...
Dendritic cells (DCs) play a critical role in the initiation, maintenance, and resolution of an immu...
Tumor-infiltrating myeloid cells, macrophages, and dendritic cells (DCs) are key regulators of tumor...
The role of endoplasmic reticulum (ER) stress in cancer has been studied in detail, and ER stress is...
Cancer cells induce a set of adaptive response pathways to survive in the face of stressors due to i...
Cancer cells induce a set of adaptive response pathways to survive in the face of stressors due to i...
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth...
Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators of immune response...
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth...
Increased protein translation in cells and various factors in the tumor microenvironment can induce ...
Metabolic, infectious and tumor cell-intrinsic noxae can all evoke the endoplasmic reticulum (ER) st...
Unresolved endoplasmic reticulum (ER) stress in the epithelium can provoke intestinal inflammation. ...
Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting tumor progress...
XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth....
XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth....
SummaryDendritic cells (DCs) are required to initiate and sustain T cell-dependent anti-cancer immun...
Dendritic cells (DCs) play a critical role in the initiation, maintenance, and resolution of an immu...
Tumor-infiltrating myeloid cells, macrophages, and dendritic cells (DCs) are key regulators of tumor...
The role of endoplasmic reticulum (ER) stress in cancer has been studied in detail, and ER stress is...
Cancer cells induce a set of adaptive response pathways to survive in the face of stressors due to i...
Cancer cells induce a set of adaptive response pathways to survive in the face of stressors due to i...
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth...
Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators of immune response...
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth...
Increased protein translation in cells and various factors in the tumor microenvironment can induce ...
Metabolic, infectious and tumor cell-intrinsic noxae can all evoke the endoplasmic reticulum (ER) st...
Unresolved endoplasmic reticulum (ER) stress in the epithelium can provoke intestinal inflammation. ...
Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting tumor progress...
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