Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor
- Onai, Takeshi
- FitzGerald, Michael G.
- Arakawa, Shoji
- Gocayne, Jeannine D.
- Urquhart, Deborah A.
- Hall, Linda M.
- Fraser, Claire M.
- McCombie, W.Richard
- Venter, J.Craig
Publication date
September 1989
DOI Publisher
Published by Elsevier B.V. ISSN
0014-5793 Citation count (estimate)
66Abstract
AbstractTwo cDNA clones (3.7 kb and 4.8 kb) encoding a Drosophila muscarinic acetylcholine receptor were isolated from a Drosophila head cDNA library and characterized by automated DNA sequence analysis. The Drosophila muscarinic receptor contains 788 amino acids with a calculated Mr of 84 807 and displays greater than 60% homology with mammalian muscarinic receptors. The muscarinic receptor maps to the tip of the right arm of the second chromosome of the Drosophila genome
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