Hepatitis C virus (HCV) is resistant to the antiviral cytokine type I interferon, representing a major clinical problem. Garaigorta and Chisari (2009) reveal that HCV uses the activation of the ds-RNA-dependent protein kinase R, which phosphorylates and inhibits the translation initiation factor eIF-2α, to block translation of interferon-stimulated genes
A stable and persistent Hepatitis C virus (HCV) replication cell culture model was developed to exam...
Taylor et al. (1) showed that the hepatitis C virus (HCV) envelope protein E2 inhibits the activity ...
AbstractInterferon alpha (IFN-α) inhibits hepatitis C virus (HCV) replication in vivo and in cell cu...
SummaryHepatitis C virus (HCV) is a single-stranded RNA virus encoding a single polyprotein whose tr...
AbstractInterferon (IFN) in combination with ribavirin is the main treatment for hepatitis C virus (...
AbstractInterferons (IFNs) induce an antiviral state in the cell through complex and indirect mechan...
AbstractHepatitis C virus (HCV) is the major cause of non-A non-B hepatitis and a leading cause of l...
Hepatitis C virus (HCV) of genotype 1 is the most resistant to interferon (IFN) therapy. Here, we ha...
International audienceHepatitis C virus is a poor inducer of interferon (IFN), although its structur...
Hepatitis C virus is a poor inducer of interferon (IFN), although its structured viral RNA can bind ...
AbstractProtein kinase R (PKR), a sensor of double-stranded RNA, plays an important role in the host...
Most isolates of hepatitis C virus (HCV) infections are resistant to interferon, the only available ...
Hepatitis C virus controls interferon production through PKR activation ARNAUD, Noella, et al. Hepat...
AbstractHepatitis C virus (HCV) has a propensity to cause chronic infection, with a low proportion o...
Interferon-alpha (IFNα) has been used to treat chronic hepatitis C virus (HCV) infection for over 20...
A stable and persistent Hepatitis C virus (HCV) replication cell culture model was developed to exam...
Taylor et al. (1) showed that the hepatitis C virus (HCV) envelope protein E2 inhibits the activity ...
AbstractInterferon alpha (IFN-α) inhibits hepatitis C virus (HCV) replication in vivo and in cell cu...
SummaryHepatitis C virus (HCV) is a single-stranded RNA virus encoding a single polyprotein whose tr...
AbstractInterferon (IFN) in combination with ribavirin is the main treatment for hepatitis C virus (...
AbstractInterferons (IFNs) induce an antiviral state in the cell through complex and indirect mechan...
AbstractHepatitis C virus (HCV) is the major cause of non-A non-B hepatitis and a leading cause of l...
Hepatitis C virus (HCV) of genotype 1 is the most resistant to interferon (IFN) therapy. Here, we ha...
International audienceHepatitis C virus is a poor inducer of interferon (IFN), although its structur...
Hepatitis C virus is a poor inducer of interferon (IFN), although its structured viral RNA can bind ...
AbstractProtein kinase R (PKR), a sensor of double-stranded RNA, plays an important role in the host...
Most isolates of hepatitis C virus (HCV) infections are resistant to interferon, the only available ...
Hepatitis C virus controls interferon production through PKR activation ARNAUD, Noella, et al. Hepat...
AbstractHepatitis C virus (HCV) has a propensity to cause chronic infection, with a low proportion o...
Interferon-alpha (IFNα) has been used to treat chronic hepatitis C virus (HCV) infection for over 20...
A stable and persistent Hepatitis C virus (HCV) replication cell culture model was developed to exam...
Taylor et al. (1) showed that the hepatitis C virus (HCV) envelope protein E2 inhibits the activity ...
AbstractInterferon alpha (IFN-α) inhibits hepatitis C virus (HCV) replication in vivo and in cell cu...
DOI
Add to ORKG