AbstractNikolaev et al. (this issue of Cell) report the identification of a parkin-like protein, Parc, and its role in anchoring the tumor suppressor protein p53 in the cytoplasm reveals yet another level of control of p53 function. Regulation of the subcellular localization of p53 by Parc may serve as a novel target in treatment of certain types of tumors
The ability to withstand mitochondrial damage is especially critical for cells such as neurons that ...
The tumor-suppressing function of p53 can be affected in a variety of manners. Here, we describe a n...
Abstractp53, can regulate cell apoptosis in both transcription-dependent and -independent manners. T...
AbstractNuclear localization of p53 is essential for its tumor suppressor function. Here, we have id...
AbstractNikolaev et al. (this issue of Cell) report the identification of a parkin-like protein, Par...
AbstractNuclear localization of p53 is essential for its tumor suppressor function. Here, we have id...
We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in c...
We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in c...
Resistance to cisplatin (CDDP)-based therapy is a major hurdle to the successful treatment of human ...
AbstractThe tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to...
A wide range of cell stresses, including DNA damage, signal to p53 through post-translational modifi...
A wide range of cell stresses, including DNA damage, signal to p53 through post-translational modifi...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65260/1/j.1432-1327.2001.02227.x.pd
Inactivation of the tumor suppressor protein p53 is a very important and common step in the process ...
The ability to withstand mitochondrial damage is especially critical for cells such as neurons that ...
The ability to withstand mitochondrial damage is especially critical for cells such as neurons that ...
The tumor-suppressing function of p53 can be affected in a variety of manners. Here, we describe a n...
Abstractp53, can regulate cell apoptosis in both transcription-dependent and -independent manners. T...
AbstractNuclear localization of p53 is essential for its tumor suppressor function. Here, we have id...
AbstractNikolaev et al. (this issue of Cell) report the identification of a parkin-like protein, Par...
AbstractNuclear localization of p53 is essential for its tumor suppressor function. Here, we have id...
We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in c...
We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in c...
Resistance to cisplatin (CDDP)-based therapy is a major hurdle to the successful treatment of human ...
AbstractThe tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to...
A wide range of cell stresses, including DNA damage, signal to p53 through post-translational modifi...
A wide range of cell stresses, including DNA damage, signal to p53 through post-translational modifi...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65260/1/j.1432-1327.2001.02227.x.pd
Inactivation of the tumor suppressor protein p53 is a very important and common step in the process ...
The ability to withstand mitochondrial damage is especially critical for cells such as neurons that ...
The ability to withstand mitochondrial damage is especially critical for cells such as neurons that ...
The tumor-suppressing function of p53 can be affected in a variety of manners. Here, we describe a n...
Abstractp53, can regulate cell apoptosis in both transcription-dependent and -independent manners. T...
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