In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human gene mutated in a form of hereditary spastic paraplegia. Spartin inhibits BMP signaling and upregulation of BMP signaling may increase microtubule stability and neurodegeneration
ABSTR ACT: Hereditary spastic paraplegia (HSP) is one of the most heterogeneous neurodegenerative di...
AbstractIn 1999, mutations in the gene encoding the microtubule severing AAA ATPase spastin were ide...
International audienceAlteration of axonal transport has emerged as a common precipitating factor in...
In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human ge...
In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human ge...
SummaryTroyer syndrome is a hereditary spastic paraplegia caused by human spartin (SPG20) gene mutat...
AbstractBackground: Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease causin...
Background: Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease causing spasti...
Nina Tang Sherwood is with California Institute of Technology, Qi Sun is with California Institute o...
<div><p>The most common form of human autosomal dominant hereditary spastic paraplegia (AD-HSP) is c...
Hereditary Spastic Paraplegia (HSP) is an adult-onset disease most commonly caused by mutation of SP...
International audienceMutations of the spastin gene (Sp) are responsible for the most frequent autos...
AbstractThe bone morphogenetic proteins (BMPs) are secreted polypeptides of the TGF-β family, whose ...
Hereditary spastic paraplegia (HSP) is characterized by weakness and spasticity of the lower limbs, ...
Impairments in intracellular transport are the hallmark of many neurological diseases including here...
ABSTR ACT: Hereditary spastic paraplegia (HSP) is one of the most heterogeneous neurodegenerative di...
AbstractIn 1999, mutations in the gene encoding the microtubule severing AAA ATPase spastin were ide...
International audienceAlteration of axonal transport has emerged as a common precipitating factor in...
In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human ge...
In this issue of Neuron, Nahm et al. (2013) examine the Drosophila ortholog of spartin, the human ge...
SummaryTroyer syndrome is a hereditary spastic paraplegia caused by human spartin (SPG20) gene mutat...
AbstractBackground: Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease causin...
Background: Hereditary Spastic Paraplegia (HSP) is a devastating neurological disease causing spasti...
Nina Tang Sherwood is with California Institute of Technology, Qi Sun is with California Institute o...
<div><p>The most common form of human autosomal dominant hereditary spastic paraplegia (AD-HSP) is c...
Hereditary Spastic Paraplegia (HSP) is an adult-onset disease most commonly caused by mutation of SP...
International audienceMutations of the spastin gene (Sp) are responsible for the most frequent autos...
AbstractThe bone morphogenetic proteins (BMPs) are secreted polypeptides of the TGF-β family, whose ...
Hereditary spastic paraplegia (HSP) is characterized by weakness and spasticity of the lower limbs, ...
Impairments in intracellular transport are the hallmark of many neurological diseases including here...
ABSTR ACT: Hereditary spastic paraplegia (HSP) is one of the most heterogeneous neurodegenerative di...
AbstractIn 1999, mutations in the gene encoding the microtubule severing AAA ATPase spastin were ide...
International audienceAlteration of axonal transport has emerged as a common precipitating factor in...
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