Synapsin I from human brain Phosphorylation by Ca2+, phospholipid-dependent protein kinase
- Severin, S.E.
- Moskvitina, E.L.
- Bykova, E.V.
- Lutzenko, S.V.
- Shvets, V.I.
DOIAbstract
AbstractSynapsin I has been isolated from human brain by a rapid and efficient purification technique, and its phosphorylation by human brain Ca2+, phospholipid-dependent protein kinase (protein kinase C) has been studied. The inhibitory effect of calmodulin on this process has been demonstrated. It is also found that non-esterified fatty acids and acidic phospholipids are inhibitory for synapsin I phosphorylation by Ca2+, calmodulin-dependent protein kinase II
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