AbstractSurfactant secretion is a critical regulated process in the metabolism of pulmonary surfactant. Presumably, because this process is vital to the survival of the organism, there are several independent pathways for stimulating secretion which work through different cell surface receptors and signaling mechanisms. In addition, there is apparent homeostatic regulation in that two components of surfactant, namely SP-A and dipalmitoylphosphatidylcholine, can inhibit secretion. Although secretion of surfactant has been studied for over two decades, there remains some important issues to be resolved. In vivo secretion can be stimulated by hyperventilation or even a single large breath. However, we do not know the biochemical mechanism for ...
AbstractSurfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted in...
SummaryThe type II cell of the pulmonary alveolus is a polarized epithelial cell that secretes surfa...
AbstractMembrane fusion between the lamellar bodies and plasma membrane is an obligatory event in th...
AbstractSurfactant secretion is a critical regulated process in the metabolism of pulmonary surfacta...
AbstractThe surfactant components saturated phosphatidylcholine, SP-B and SP-C, are secreted togethe...
AbstractPulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial...
AbstractTwo small, hydrophobic peptides, surfactant protein (SP)-B and SP-C, play important roles in...
AbstractSurfactant protein A (SP-A) has been shown to bind to and regulate the functions of both alv...
Lung surfactant reduces surface tension and maintains the stability of alveoli. How surfactant is re...
The pulmonary surfactant is a lipid/protein complex that diminishes surface tension forces and facil...
5-22Surfactant is an agent that decreases the surface tension between two media. The surface tensio...
doi:10.1152/ajplung.00066.2010.—Alveolar surfactant protein A (SP-A) is endocytosed by type II epith...
AbstractSurfactant protein B is a small homodimeric protein that is found tightly associated with su...
The molecular basis involving adsorption of pulmonary surfactant at the respiratory air–liquid inter...
We studied secretion of surfactant protein A(SP-A) and D(SP-D) from isolated alveolar type II cells ...
AbstractSurfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted in...
SummaryThe type II cell of the pulmonary alveolus is a polarized epithelial cell that secretes surfa...
AbstractMembrane fusion between the lamellar bodies and plasma membrane is an obligatory event in th...
AbstractSurfactant secretion is a critical regulated process in the metabolism of pulmonary surfacta...
AbstractThe surfactant components saturated phosphatidylcholine, SP-B and SP-C, are secreted togethe...
AbstractPulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial...
AbstractTwo small, hydrophobic peptides, surfactant protein (SP)-B and SP-C, play important roles in...
AbstractSurfactant protein A (SP-A) has been shown to bind to and regulate the functions of both alv...
Lung surfactant reduces surface tension and maintains the stability of alveoli. How surfactant is re...
The pulmonary surfactant is a lipid/protein complex that diminishes surface tension forces and facil...
5-22Surfactant is an agent that decreases the surface tension between two media. The surface tensio...
doi:10.1152/ajplung.00066.2010.—Alveolar surfactant protein A (SP-A) is endocytosed by type II epith...
AbstractSurfactant protein B is a small homodimeric protein that is found tightly associated with su...
The molecular basis involving adsorption of pulmonary surfactant at the respiratory air–liquid inter...
We studied secretion of surfactant protein A(SP-A) and D(SP-D) from isolated alveolar type II cells ...
AbstractSurfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted in...
SummaryThe type II cell of the pulmonary alveolus is a polarized epithelial cell that secretes surfa...
AbstractMembrane fusion between the lamellar bodies and plasma membrane is an obligatory event in th...