Degradation of α-actinin during Ca2+-sensitive proteolysis of myofibrils

AbstractThe noted loss of α-actinin from the Z-line of myofibrils during post-mortem autolysis, probably following the action of calcium-activated protease, has previously been attributed to its release without degradation. This report shows that in isolated myofibrils α-actinin is proteolysed in a Ca2+-sensitive manner presumably via the action of calcium-activated protease