982-116 Gender-related Differences in Risk Factors of Young Patients with Symptomatic Coronary Artery Disease

732 consecutive patients (pts)≤55 years old admitted to a tertiary care facility with symptomatic coronary artery disease (SCAD) were evaluated to determine if there were gender-related differences in risk factors (RF) for SCAD. Personal health perceptions, laboratory values, and physical measurements were obtained on 141 females (19%) and 591 males (81%) pts.Risk FactorsMenWomenChi-square%%male vs female (p value)1. Current Smoking37%43%0.242. High Blood Pressure25%28%0.393. Family Hx of Heart Dz31%34%0.51(1 st degree relative <55)4. Diabetes11%26%<0.0015. Sedentary Lifestyle75%86%0.0366. Total Cholesterol >240mg/dl28%42%0.0037. Increased Waist–Hip Ratio78%75%0.48male≥0.95, female≥>0.85Females had more RF than males (mean 3.26 vs 2.87, p=0.009) and 50% of females had≥4 RF compared with 30% of males (p<0,001). Menopause [natural (49), surgical (8)] was reported in 57 female pts (40%). 14 (25%) of these post-menopausal females were receiving estrogen replacement therapy (ERT).ConclusionIn this cohort of young pts with SCAD, females had more frequent incidence of diabetes and severe hyperlipidemia, were more sedentary, and had multiple RF more often than males. Few post-menopausal females in this high risk group received ERT. RF intervention programs focusing on the special needs of female pts with SCAD are needed