Myc/Max complexes are thought to be essential for maintaining pluripotency and self-renewal of embryonic stem cells (ESCs). In this issue of Cell Stem Cell, Hishida et al. (2011) provide genetic evidence that this requirement can be bypassed in well-defined culture conditions
There is much interest in understanding the signals in the bone marrow niche that keep hematopoietic...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cel...
SummaryCanonical Wnt signaling regulates the self-renewal of most if not all stem cell systems. In t...
Adult stem cells hold great promise for regenerative medicine, yet it is difficult to expand such ce...
Wnt proteins are known to signal via canonical β-catenin-mediated and non-canonical β-catenin-indepe...
There is near consensus that Wnt family molecules establish important gradients within niches where ...
Stem cell self-renewal is intrinsically associated with cell cycle control. However, the precise mec...
Embryonic stem cells (ESCs) are prone to differentiation in culture, suggesting that maintenance of ...
SummaryAll mature blood cell types in the adult animal arise from hematopoietic stem and progenitor ...
SummaryHuman embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equ...
markdownabstract__Abstract__ Mammalian development starts from a fertilized egg that initially ge...
The understanding of pluripotent stem cells at a molecular level and progress toward applying these ...
Every day, billions of new blood cells are produced in the body, each one derived from a hematopoiet...
There is much interest in understanding the signals in the bone marrow niche that keep hematopoietic...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cel...
SummaryCanonical Wnt signaling regulates the self-renewal of most if not all stem cell systems. In t...
Adult stem cells hold great promise for regenerative medicine, yet it is difficult to expand such ce...
Wnt proteins are known to signal via canonical β-catenin-mediated and non-canonical β-catenin-indepe...
There is near consensus that Wnt family molecules establish important gradients within niches where ...
Stem cell self-renewal is intrinsically associated with cell cycle control. However, the precise mec...
Embryonic stem cells (ESCs) are prone to differentiation in culture, suggesting that maintenance of ...
SummaryAll mature blood cell types in the adult animal arise from hematopoietic stem and progenitor ...
SummaryHuman embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equ...
markdownabstract__Abstract__ Mammalian development starts from a fertilized egg that initially ge...
The understanding of pluripotent stem cells at a molecular level and progress toward applying these ...
Every day, billions of new blood cells are produced in the body, each one derived from a hematopoiet...
There is much interest in understanding the signals in the bone marrow niche that keep hematopoietic...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
Hematopoietic stem cells (HSCs) can self renew and differentiate into all cell types of the blood. T...
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